A Serosurvey of Borna Disease Virus Infection in Wild Rats by a Capture ELISA
نویسندگان
چکیده
منابع مشابه
The immunopathogenesis of Borna disease virus infection.
Borna disease virus (BDV) infection represents an excellent model system to study immunopathological mechanisms based on a T cell-mediated immune reaction in the central nervous system. The single-stranded RNA Borna disease virus, a member of Bornaviridae in the order of Mononegavirale, lacks cytopathogenicity both in vitro and in vivo. After experimental infection BDV causes a persistent infec...
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Borna disease virus (BDV) is a nonsegmented, negative-, single-stranded, highly neurotropic RNA virus with noncytolytic replication in the central nervous system. This virus causes neurological and behavioral disturbances primarily in horses and sheep, in addition to a variety of other vertebrate animal species and in laboratory animal models. BDV is now gaining much of the research attention, ...
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Borna Disease Virus infection (BDV) is a well known animal disease. It got its name from a disease outbreak among horses around the small town ‘‘Borna’’, 26 km south-east of Leipzig in the late 19th century. The symptoms in horses have been described in detail and involve neurologic as well as mental and behavioral disorders. A long debate exists whether or not human infections do exist. Severa...
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The mechanisms whereby Borna disease virus (BDV) can impair neuronal function and lead to neurobehavioral disease are not well understood. To analyze the electrophysiological properties of neurons infected with BDV, we used cultures of neurons grown on multielectrode arrays, allowing a real-time monitoring of the electrical activity across the network shaped by synaptic transmission. Although i...
متن کاملBorna disease virus infection, a human mental-health risk.
This article focuses on human Borna disease virus (BDV) infections, most notably on the development of valid diagnostic systems, which have arisen as a major research issue in the past decade. The significance of a novel modular triple enzyme-linked immunosorbent assay that is capable of specifically measuring anti-BDV antibodies as well as major structural proteins N (p40) and P (p24) in the b...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1999
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.61.113